Fat embolism syndrome: choice and effectiveness of laboratory diagnostic methods

Authors

  1. Burdenko Main Military Clinical Hospital, Moskva, Russian Federation
  2. Russian Medical Academy of Continuous Postgraduate Education, Moskva, Russian Federation
  3. Moscow Medical - Social Institute named after Friedrich Haass, Moskva, Russian Federation
  4. Moscow State University of Food Production, Moskva, Russian Federation

https://doi.org/10.35571/RMSJ.2019.2.006

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Abstract

The review on the use of traditional and new methods of laboratory diagnostics of fat embolism syndrome - a complication that in some cases asymptomatically accompanies severe concomitant trauma is presented. The main currently used laboratory diagnostic methods are described: traditional methods and new markers (interleukin-6, neuroglial protein S100B, surfactant protein SP-D). A review of the literature data in terms of assessing the pathogenetic and diagnostic significance of some methods of laboratory diagnosis of fat embolism syndrome, the relationship between the dynamics of the considered laboratory parameters, the clinical picture and inflammation. Own observation is presented. The results show the importance of integrating the whole range of available methods in the diagnosis of fat embolism syndrome.

Keywords

multiple trauma, multiple fractures, fat embolism syndrome, inflammation, laboratory diagnosis, microscopy, fat globulinemia, IL-6, CRP

Для цитирования:

Карпов В.О., Клеина И.В., Казаков С.П., Корабельников Д.И., Гизатуллин Ш.Х. Синдром жировой эмболии: выбор и эффективность методик лабораторной диагностики. Российский медико-социальный журнал. 2019;1(2):71-82. https://doi.org/10.35571/RMSJ.2019.2.006

For citation:

Karpov V., Kleina I., Kazakov S.P., Korabelnikov D., Gizatullin S. Fat embolism syndrome: choice and effectiveness of laboratory diagnostic methods. Russian Medical and Social Journal. 2019;1(2):71-82. (In Russian) https://doi.org/10.35571/RMSJ.2019.2.006

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About the authors

  • Vladimir Karpov, Burdenko Main Military Clinical Hospital, Moskva, Russian Federation

    Burdenko Main Military Clinical Hospital — Emergency Laboratory Unit, Clinical Laboratory Diagnostics Center, Chief

  • Irina Kleina, Burdenko Main Military Clinical Hospital, Moskva, Russian Federation

    Burdenko Main Military Clinical Hospital — Cytogenetic and Cytochemical Research Laboratory of the Clinical Hematological Research Dept, Clinical Laboratory Diagnostics Center, Chief of the Laboratory

  • Sergey P. Kazakov, Burdenko Main Military Clinical Hospital, Moskva, Russian Federation, Russian Medical Academy of Continuous Postgraduate Education, Moskva, Russian Federation

    Burdenko Main Military Clinical Hospital — Clinical Laboratory Diagnostics Center, Head of the Center

    Russian Medical Academy of Continuous Postgraduate Education — Immunology Dept, Head of the Dept

  • Daniil Korabelnikov, Moscow Medical - Social Institute named after Friedrich Haass, Moskva, Russian Federation

    Moscow Medical - Social Institute named after Friedrich Haass — Rector

  • Shamil' Gizatullin, Burdenko Main Military Clinical Hospital, Moskva, Russian Federation, Moscow State University of Food Production, Moskva, Russian Federation

    Burdenko Main Military Clinical Hospital — Neurosurgery Dept, Head of the Dept

    Moscow State University of Food Production — Surgery Dept, Medical Institute of Continuing Education, Professor

How to Cite

Fat embolism syndrome: choice and effectiveness of laboratory diagnostic methods. (2019). Russian Medical and Social Journal, 1(2), 71-82. https://doi.org/10.35571/RMSJ.2019.2.006
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