Imaging in diagnostics and management of extramedullary lesions in a patient with multiple myeloma

Authors

  1. Burdenko Main Military Clinical Hospital, Moskva, Russian Federation
  2. Moscow Medical - Social Institute named after Friedrich Haass, Moskva, Russian Federation
  3. Main Military Hospital named after N.Burdenko under The Ministry of Defence of The Russian Federation, Moskva

https://doi.org/10.35571/RMSJ.2019.1.007

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Abstract

Extraosseous manifestations are found in less than 5% of patients with multiple myeloma. Involvement of the gastrointestinal system in the course of multiple myeloma (MM) is extremely rare. Imaging is required for correct staging, in the followup after treatment and is predictor of prognosis. Several imaging technologies are used for the diagnosis and management of patients with MM. Conventional radiography, computed tomography (CT), magnetic resonance imaging (MRI) and nuclear medicine imaging - positron emission tomography (PET) combined with CT (PET/CT) and PET combined with MRI (PET/MRI) are all used in clarifying the extent of bone and soft tissue lesions in MM. The brief literature review on extramedullary lesions in MM and their imaging with recommendations is given. We describe the imaging in diagnostics and management of an rare case of secondary extramedullary plasmacytoma (EMP) in relapse involving the pancreas and duodenum with the bleeding in a patient with MM, IgA lambda, stage II, after 6-years treatment with chemotherapy, autologous peripheral blood stem cell transplantation and radiotherapy. EMP was detected by PET/CT before the appearance of obvious clinical signs, and then EMP was monitoring by PET/CT, X-ray and ultrasound.

Keywords

Myeloma, Extramedullary plasmacytoma, Pancreas, Duodenum, Imaging, Magnetic Resonance imaging, Computer tomography, Positron Emission tomography, X-ray, Radiation diagnostics, Ulrasound

Для цитирования:

Козырев С.В., Корабельников Д.И., Поп В.П., Троян В.Н., Рукавицын О.А. Лучевая диагностика экстрамедуллярных поражений у пациента со множественной миеломой. Российский медико-социальный журнал. 2019;1(1):74-87. https://doi.org/10.35571/RMSJ.2019.1.007

For citation:

Kozyrev S., Korabelnikov D., Pop V., Troyan V., Rukavicyn O.A. Imaging in diagnostics and management of extramedullary lesions in a patient with multiple myeloma. Russian Medical and Social Journal. 2019;1(1):74-87. (In Russian) https://doi.org/10.35571/RMSJ.2019.1.007

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About the authors

  • Sergey Kozyrev, Burdenko Main Military Clinical Hospital, Moskva, Russian Federation

    Burdenko Main Military Clinical Hospital — X-ray diagnostics unit of the Radiodiagnosics Dept, Head of the X-ray diagnostics unit - deputy head of the Radiodiagnosics Dept

  • Daniil Korabelnikov, Moscow Medical - Social Institute named after Friedrich Haass, Moskva, Russian Federation

    Moscow Medical - Social Institute named after Friedrich Haass — Rector

  • Vasiliy Pop, Burdenko Main Military Clinical Hospital, Moskva, Russian Federation

    Burdenko Main Military Clinical Hospital — Hematology unit of the Hematology Center, Head of the Hematology unit

  • Vladimir Troyan, Burdenko Main Military Clinical Hospital, Moskva, Russian Federation

    Burdenko Main Military Clinical Hospital — Radiodiagnosics Dept, Head of the Radiodiagnosics Dept, Chief radiologist

  • Oleg A. Rukavicyn, Main Military Hospital named after N.Burdenko under The Ministry of Defence of The Russian Federation, Moskva

    Main Military Hospital named after N.Burdenko under The Ministry of Defence of The Russian Federation — Hematology dept, Head of the Dept - Chief hematologist of The Hospital

How to Cite

Imaging in diagnostics and management of extramedullary lesions in a patient with multiple myeloma. (2019). Russian Medical and Social Journal, 1(1), 74-87. https://doi.org/10.35571/RMSJ.2019.1.007
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ISSN (Print) 2658-7726 ISSN (Online) 2658-7718